In Hungary, the number of apiaries reaches 20,000, and it takes 10% of the total honey production of the EU. The maintenance of the health of the bee colonies is a key issue for the beekeepers and it is also essential from the view of the ecological aspect of bee pollinating. Our aim is to examine how the probiotics - mainly the inulin - effects on the intestinal microbiome of the bees and on the honey quality. After the inulin feedings of the bees, the quantity and quality changes of the certain microbes are examined. For this purpose, micro-, and molecular biological and metagenomic analysis are also applied.